New biologic drug ASKG915 enters human trials for Hard-to-Treat cancers
NCT ID NCT05867420
First seen Jan 31, 2026 · Last updated Jun 22, 2026 · Updated 17 times
Summary
This study tests a new biologic drug called ASKG915, given alone or with standard chemotherapy, in about 594 people with advanced solid tumors that no longer respond to available treatments. The main goals are to check the drug's safety and how the body processes it. The trial is currently recruiting participants.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Columbia University Irving Medical Center
RECRUITINGNew York, New York, 10032, United States
Contact
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Fudan University Shanghai Cancer Center
RECRUITINGShanghai, Shanghai Municipality, 201321, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Peking University Cancer Hospital
NOT_YET_RECRUITINGBeijing, Beijing Municipality, 100089, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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UPMC Hillman Cancer Center
RECRUITINGPittsburgh, Pennsylvania, 15232, United States
Contact
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
ASKG915 (a biologic drug given intravenously)
What this could lead to
If successful, this could lead to a new treatment option for people with advanced solid tumors that have stopped responding to other therapies.
What could go wrong
This is an early-phase trial focused on safety and dosing, so it is not yet known if ASKG915 will effectively shrink tumors or improve survival. Side effects are possible and being studied.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.