Simple blood test may predict artery health and heart attack risk
NCT ID NCT07589374
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at how metabolic health (measured by a simple blood test) relates to artery stiffness and daily blood pressure changes in 800 adults. Researchers will use routine tests and non-invasive measurements to find better ways to identify people at higher risk for heart disease. No treatments are given—only data collection from standard care.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 800 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jul 2026
An estimate. Start dates often move.
- Expected to finish
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Jul 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The study population will consist of adults aged 18 to 65 years referred for ambulatory blood pressure monitoring (ABPM) as part of routine clinical evaluation at a specialized cardiovascular center. Participants will include both normotensive individuals and untreated hypertensive individuals, classified based on 24-hour ABPM measurements. The study will include both previously collected data and prospectively recruited participants evaluated using standardized protocols.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults aged 18 to 65 years; * Both sexes; * Referred for ambulatory blood pressure monitoring (ABPM) as part of routine clinical evaluation; * Not receiving antihypertensive medication at the time of assessment; * Availability of valid 24-hour ABPM data; * Availability of carotid-femoral pulse wave velocity (cf-PWV) measurement; * Availability of fasting laboratory data, including glucose and triglycerides, for calculation of the triglyceride-glucose (TyG) index; * Ability and willingness to provide written informed consent (for prospectively recruited participants). Exclusion Criteria: * Use of antihypertensive medication at the time of evaluation; * Cardiac arrhythmias that may interfere with accurate blood pressure or pulse wave velocity measurements; * Invalid or poor-quality ambulatory blood pressure monitoring (ABPM) recordings; * Inability to obtain reliable carotid-femoral pulse wave velocity (cf-PWV) measurements; * Presence of severe vascular disease or conditions affecting arterial waveform assessment; * Missing essential clinical, laboratory, or hemodynamic data required for the primary analysis; * Pregnancy; * Refusal or inability to provide informed consent (for prospectively recruited participants).
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Medicine School of São José do Rio Preto
São José do Rio Preto, São Paulo, 15090-000, Brazil
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