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Parkinson's gene link: sleep and symptoms under the microscope

NCT ID NCT04553185

First seen Nov 01, 2025 · Last updated May 20, 2026 · Updated 21 times

Summary

This study looked at 733 people with Parkinson's disease to see if certain genetic changes in the AQP4 gene are linked to worse motor, cognitive, and sleep symptoms. Researchers measured these gene variations and compared them to symptom severity. The goal was to better understand how genes influence the course of Parkinson's, not to test a new treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • East Kent University Hospitals NHS Foundation Trust

    Ashford, United Kingdom

  • Lewisham and Greenwich NHS Foundation Trust

    London, United Kingdom

  • Prince Phillip Hospital

    Llanelli, United Kingdom

  • University of Exeter

    Exeter, SE16 7RJ, United Kingdom

Conditions

Explore the condition pages connected to this study.