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New hope for mouth sore sufferers: safer drug combo tested

NCT ID NCT06260904

First seen Jan 11, 2026 · Last updated Apr 29, 2026 · Updated 17 times

Summary

This study tested two different drugs, apremilast and methotrexate, added to standard steroid treatment for people with oral lichen planus, a painful inflammatory mouth condition. The goal was to see which drug works better and has fewer side effects, since long-term steroid use can be harmful. 64 adults who did not improve with topical steroids took part in this head-to-head comparison over 12 weeks.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • AIIMS Bhubaneswar

    Bhubaneswar, Odisha, 751019, India

Conditions

Explore the condition pages connected to this study.