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New drug combo targets stubborn blood cancers in early trial

NCT ID NCT04496349

First seen Nov 04, 2025 · Last updated May 01, 2026 · Updated 23 times

Summary

This study tests two experimental drugs, APG-115 and APG-2575, alone or together, in adults with relapsed or refractory T-cell prolymphocytic leukemia (T-PLL) or non-Hodgkin's lymphoma (NHL). The goal is to find safe doses and see if the drugs can shrink tumors or control the disease. About 78 participants will join this phase 2 trial.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • MD Anderson

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.