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ICU superbug study reveals resistance patterns

NCT ID NCT07172932

Knowledge-focused Sponsor: Ankara City Hospital Bilkent Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This completed study looked at 314 ICU patients with bloodstream infections caused by Enterobacterales bacteria. Researchers identified how often these bacteria were resistant to common antibiotics and what patient factors increased the risk. The goal was to understand resistance patterns to help guide better treatment decisions.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help doctors better identify and manage antibiotic-resistant infections in ICU patients, potentially reducing deaths.
What could go wrong
This is a completed observational study, not a treatment trial. It only identifies risk factors and resistance patterns, so it cannot directly improve patient outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

314 people

The number who actually took part.

Started

Sep 2019

Finished

Jan 2023

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

This retrospective study included adult patients who were hospitalized in the intensive care units (ICUs) of the Neurology-Orthopedics Building at Ankara City Hospital between September 2019 and December 2022. Eligible participants were aged 18 years or older and had a blood culture positive for Enterobacterales species during ICU stay, which was evaluated by an Infectious Diseases and Clinical Microbiology specialist as the causative pathogen.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age ≥ 18 years * Isolation of an Enterobacterales species from a blood culture obtained during ICU stay * The isolate considered as the causative pathogen by an Infectious Diseases and Clinical Microbiology specialist Exclusion Criteria: * Isolates not considered as causative pathogens * Growth of a different pathogen in blood culture within ±72 hours of the index culture

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Conditions

The condition(s) this trial relates to.

bacterial infectious disease with sepsis Enterobacteriaceae Infections Sepsis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Antibiotic resistant infection Bloodstream infections Enterobacteriaceae infections Intensive care (ICU)

Contacts and locations

Locations

  • Ankara Bilkent City Hospital

    Çankaya, Ankara, 06800, Turkey (Türkiye)

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