Painkiller may also fight bacteria in PCA pumps
NCT ID NCT07285759
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This lab study tested whether levobupivacaine, a local anesthetic used in patient-controlled analgesia (PCA) pumps, can kill Staphylococcus aureus bacteria. Researchers mixed the drug at two common concentrations with bacteria in a lab model and counted how many bacteria survived. The goal is to see if the anesthetic itself might help prevent infections in patients using these pain pumps.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Levobupivacaine
- What this could lead to
- If levobupivacaine shows strong antibacterial effects, it could help reduce infection risk in patients using PCA pumps for pain relief.
- What could go wrong
- This is a small lab study, not a human trial. Results may not translate to real-world use, and the effect might be too weak to matter clinically.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
40 people
The number who actually took part.
- Started
-
Nov 2010
- Finished
-
Feb 2011
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Laboratory study using Staphylococcus aureus bacterial cultures. * Samples exposed to different concentrations of levobupivacaine and fentanyl solutions. * Controlled laboratory environment (Dokuz Eylül University, Microbiology Laboratory). Exclusion Criteria: * No human participants included. * No animal models used. * Studies outside the defined experimental conditions were excluded.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.