Can your diet calm rheumatoid arthritis? new study aims to find out
NCT ID NCT04748809
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is testing whether an anti-inflammatory diet can help people with rheumatoid arthritis feel better and reduce disease activity. Researchers will compare two different anti-inflammatory diets in 124 adults with low to moderate disease activity. The goal is to see if diet changes can lead to a meaningful drop in symptoms and inflammation.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- anti-inflammatory diet
- What this could lead to
- If it works, this could provide a simple dietary option to help manage rheumatoid arthritis symptoms and reduce disease activity.
- What could go wrong
- This is a relatively small early-stage trial with no blinding for diet, so results may be influenced by placebo effects. The diet may not work for everyone and could be hard to follow long-term.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 124 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Nov 2020
- Expected to finish
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Mar 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients with low or moderate disease activity (defined as Clinical Disease Activity Index ≤ 22) and without changes in disease activity or therapy during the previous 3 months, who are interested in dietary intervention, and are able to provide consent and attend to follow up visits. Exclusion Criteria: * Pregnancy or lactating. Patients that will become pregnant during the study will be remove from the study. * Food allergies * Subjects with significant other comorbidities and /or medication use which in physician's clinical judgment might difficult the interpretation of the results
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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UCSD
RECRUITINGLa Jolla, California, 92093, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- A new ankle? researchers track 400 people with an implant meant to restore movement
- Can a Job-Focused rehab program keep arthritis patients employed?
- Do rheumatic diseases quietly damage the Eye's oil glands?
- Hidden kidney damage may lurk in rheumatoid arthritis patients
- Can a new injection calm rheumatoid arthritis? an early trial puts ZB002 to the test