Engineered immune cells take on recurrent brain tumors in first human trial
NCT ID NCT06964737
First seen Nov 01, 2025 · Last updated May 22, 2026 · Updated 32 times
Summary
This early-phase study tests a new treatment called anti-GARP CAR T-cell therapy for people with recurrent high-grade glioma, a type of aggressive brain cancer. The therapy involves taking a patient's own immune cells, modifying them in a lab to recognize and attack cancer cells, and infusing them back. The main goals are to find the safest dose and understand side effects in up to 30 adults.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Ohio State University Comprehensive Cancer Center
RECRUITINGColumbus, Ohio, 43210, United States
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