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Wrinkle-Fighting collagen injection shows promise in small study

NCT ID NCT06152718

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tested a new medical device that injects a special type of collagen into the skin to reduce wrinkles and improve skin quality. One hundred adults with mild to severe skin aging received the injections and were followed for 60 days. Researchers measured changes in wrinkle depth, skin color, and patient satisfaction.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
single-strand alpha-1 collagen in a hyaluronic acid and carboxymethylcellulose matrix
What this could lead to
If it works, this could offer a new, minimally invasive option for reducing wrinkles and improving skin appearance.
What could go wrong
This is a small, completed study with no control group, so results may not be generalizable. The effects are cosmetic and temporary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

100 people

The number who actually took part.

Started

Dec 2023

Finished

Dec 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 65 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age range 20-65 years old * skin ageing evidences from mild to severe Inclusion Criteria: * not affected by oncological diseases * rheumatological diseases * no allergic diseases * no chronic inflammatory diseases (including dermatitis, psoriasis, etc.). Patients should not have; * metabolic diseases * cardiovascular diseases, * should not have received other injections of hyaluronic acid or similar substances for at least 6 months before the start of treatment, * should not take systemic drugs during the study

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Conditions

The condition(s) this trial relates to.

Inflammation Skin Manifestations

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • NabBio

    Palermo, PA, 90141, Italy

  • University of Novi Sad, Serbia

    Novi Sad, Serbia, 21000, Serbia

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Other studies related to the condition(s) this trial covers.