Wrinkle-Fighting collagen injection shows promise in small study
NCT ID NCT06152718
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study tested a new medical device that injects a special type of collagen into the skin to reduce wrinkles and improve skin quality. One hundred adults with mild to severe skin aging received the injections and were followed for 60 days. Researchers measured changes in wrinkle depth, skin color, and patient satisfaction.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- single-strand alpha-1 collagen in a hyaluronic acid and carboxymethylcellulose matrix
- What this could lead to
- If it works, this could offer a new, minimally invasive option for reducing wrinkles and improving skin appearance.
- What could go wrong
- This is a small, completed study with no control group, so results may not be generalizable. The effects are cosmetic and temporary.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
100 people
The number who actually took part.
- Started
-
Dec 2023
- Finished
-
Dec 2024
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
20 to 65 years
- Sex
-
Anyone
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age range 20-65 years old * skin ageing evidences from mild to severe Inclusion Criteria: * not affected by oncological diseases * rheumatological diseases * no allergic diseases * no chronic inflammatory diseases (including dermatitis, psoriasis, etc.). Patients should not have; * metabolic diseases * cardiovascular diseases, * should not have received other injections of hyaluronic acid or similar substances for at least 6 months before the start of treatment, * should not take systemic drugs during the study
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Skin manifestations are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
NabBio
Palermo, PA, 90141, Italy
-
University of Novi Sad, Serbia
Novi Sad, Serbia, 21000, Serbia
More trials for these conditions
Other studies related to the condition(s) this trial covers.