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Ankle sprain secrets revealed: Athletes' muscles and balance under the microscope

NCT ID NCT07579793

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
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Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at 60 athletes to understand how past ankle sprains affect muscle size, ligament thickness, balance, and strength. Researchers compared athletes with and without a history of ankle sprains using ultrasound and balance tests. The goal is to find early warning signs that could help prevent future sprains.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

60 people

The number who actually took part.

Started

May 2025

Finished

May 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

This study is a retrospective, cross-sectional investigation conducted to evaluate the relationship between intrinsic risk factors, including muscle and ligament sizes, dynamic balance, postural stability, proprioception and ankle instability in athletes diagnosed with chronic ankle instability (CAI). Participants will be equally recruited into the group with athletes who have a lateral ankle sprain history (LAS Group) and the Control group, with consideration for gender stratification (groups will have the same number of males and females).

Ages

18 to 35 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. At least 5 years of active participation in any sport. 2. Age between 18 and 35. 3. A history of at least two clinically diagnosed LAS episodes with inflammatory symptoms like pain and swelling. 4. The last sprain occurred at least 3 months before the study start, and the participant has fully returned to their sport. 5. No previous surgeries affecting Exclusion Criteria: 1. Any history of ankle fracture. 2. Surgery or systemic disease impacting sensorimotor function in the lower limb. 3. Neurological disorders. 4. Recent (within a month) acute injury to the lower extremity. 5. Visual or vestibular issues that impair balance or coordination.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Medipol University

    Istanbul, Turkey (Türkiye)

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