Knee surgery may change ankle pain – small study investigates
NCT ID NCT05183750
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study looked at 20 people with knee arthritis who had a surgery called high tibial osteotomy (HTO) to realign their knee. The goal was to see how the surgery changed ankle pain and ankle joint alignment. Researchers measured pain and bone angles before and after surgery. The study is complete, but because it is small and observational, it only helps us understand possible links, not prove a treatment works.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- high tibial osteotomy (surgical procedure)
- What this could lead to
- If successful, this could help doctors understand how knee surgery affects the ankle, potentially improving surgical planning and reducing ankle pain after knee realignment.
- What could go wrong
- This is a very small, completed study with only 20 participants. It does not test a new treatment, so results may not apply to everyone and cannot confirm any benefits.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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20 people
The number who actually took part.
- Started
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Dec 2021
- Finished
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Sep 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 55 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Symptomatic medial unicompartment knee arthritis * Active patients younger than 55 years * Good range of motion (ROM) . * Intact lateral compartment Exclusion Criteria: * Combined medial and lateral arthrosis. * Markedly decreased knee range of motion (arc of motion 10°). * Ligamentous instability. * Severe joint destruction (≥Ahlback grade III). * ≥55 years of age. * Advanced patellofemoral arthritis. * Rheumatoid arthritis. * Structural lower extremity deformities. * Previous operation at knee joint.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Sohag univeristy- Faculty of medicine
Sohag, 82511, Egypt
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Other studies related to the condition(s) this trial covers.