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Which anesthesia helps you wake up smoother after spine surgery?

NCT ID NCT07123870

Symptom relief Sponsor: Kocaeli City Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 05, 2026 · Last updated Aug 06, 2026 · Updated 1 time

Summary

This trial tests three common anesthesia methods in adults having long spine surgery (over three hours) to see which one leads to the quickest and most comfortable recovery. The methods are total intravenous anesthesia (TIVA) alone, TIVA combined with sevoflurane, and TIVA combined with desflurane. Researchers will measure how fast patients wake up, how soon they can breathe on their own, and how quickly they leave the recovery room, as well as any nausea or agitation after surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Three anesthesia approaches: total intravenous anesthesia (TIVA), TIVA plus sevoflurane, and TIVA plus desflurane.
What this could lead to
If one method proves better, it could guide anesthesia choices to help patients wake faster and recover more comfortably after long surgeries.
What could go wrong
This is a single-center trial, and results may not apply to all hospitals or surgeries. Individual patient factors can also affect recovery, so no single method may emerge as clearly superior.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

210 people

The number who actually took part.

Started

Jul 2025

Finished

Nov 2025

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Scheduled for spine surgery * Expected surgery duration longer than 3 hours * Use of intraoperative neuromonitoring * BIS-guided anesthesia administered * TIVA (with TCI) as the primary anesthetic technique * Age \>18 years Exclusion Criteria: * Emergency surgeries * Patients receiving sole inhaled anesthesia (no TIVA) * Perioperative dural injury * Intraoperative severe hypotension requiring inotropic support * Hypothermia (based on temperature measured before recovery)

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Inhalation anesthesia Postoperative recovery Total intravenous anesthesia

Contacts and locations

Locations

  • Kocaeli City Hospital

    Kocaeli, Izmıt, Yozgat, Turkey (Türkiye)

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