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Could the type of anesthesia affect kidney transplant success?

NCT ID NCT07678073

Knowledge-focused Sponsor: University of Gaziantep Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 01, 2026 · Last updated Jul 09, 2026 · Updated 3 times

Summary

This study compares two anesthesia methods—general anesthesia with sevoflurane and combined spinal-epidural anesthesia—in adults receiving a kidney transplant. Researchers will measure blood markers related to cell damage and protection to see if one method better shields the new kidney from injury. The goal is to understand how anesthesia choice might influence early graft function and recovery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Sevoflurane (general anesthetic) and combined spinal-epidural anesthesia
What this could lead to
If one anesthesia method better protects the new kidney from injury, it could improve transplant success and long-term function.
What could go wrong
This is a small, early-stage study measuring blood markers, not direct patient outcomes. Results may not lead to changes in practice.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 68 people

The number the study aims to enrol. It can still change while the study runs.

Started

Mar 2026

Expected to finish

Oct 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 70 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients aged 18-70 years with American Society of Anesthesiologists (ASA) physical status I-III. * Patients scheduled for elective living-donor allogeneic kidney transplantation. * Patients receiving sevoflurane-based general anesthesia as the anesthetic technique. * Patients receiving combined spinal-epidural anesthesia as the anesthetic technique. Exclusion Criteria: * Patients younger than 18 years or older than 70 years. * Patients undergoing deceased-donor kidney transplantation. * Patients receiving total intravenous anesthesia (TIVA). * Patients who decline to participate in the study or are unable to provide informed consent. * Patients with American Society of Anesthesiologists (ASA) physical status IV or V. * Patients with a history of previous organ transplantation. * Patients with known or suspected mitochondrial disorders. * Patients with a history of chronic corticosteroid use. * Patients requiring red blood cell transfusion intraoperatively or within the first 24 postoperative hours. * Patients with a primary warm ischemia time \>5 minutes, secondary warm ischemia time \>30 minutes, or cold ischemia time \>60 minutes.

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Conditions

The condition(s) this trial relates to.

chronic kidney disease end stage renal failure impaired renal function disease kidney disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

KIDNEY Kidney disease Kidney disease, end-stage Kidney transplant Renal transplant

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

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Contacts and locations

Locations

  • Gaziantep University Faculty of Medicine Hospital

    RECRUITING

    Gaziantep, State/Province, 27310, Turkey (Türkiye)

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