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Which anesthesia is safest for obese Patients' brains after surgery?

NCT ID NCT07665645

Knowledge-focused Sponsor: Gaziantep City Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at how different types of anesthesia affect thinking and memory after surgery in 90 obese patients. Some received sevoflurane gas at low or normal flow, others received intravenous anesthesia. Researchers tested their mental function before surgery, 30 minutes after, and three days later. The goal is to find which method best protects brain health in obese patients undergoing abdominal surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
sevoflurane, propofol, remifentanil
What this could lead to
If successful, this could help doctors choose the best anesthesia for obese patients to protect their memory and thinking after surgery.
What could go wrong
This is a small, completed study with 90 patients, so results may not apply to everyone. The cognitive test used is simple and may miss subtle changes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

90 people

The number who actually took part.

Started

Jan 2023

Finished

Jun 2023

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age between 18 and 65 years * Body mass index (BMI) ≥30 kg/m² * ASA physical status I-III * Scheduled for elective laparoscopic abdominal surgery * Provision of written informed consent Exclusion Criteria: * History of psychiatric disease * Dementia or known cognitive impairment * Hearing or language disorders preventing MMSE assessment * Refusal to participate * Conversion from laparoscopic to open surgery

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Obesity (bmi>30) Postoperative cognitive function

Contacts and locations

Locations

  • Marmara University Faculty of Medicine Pendik Training and Research Hospital

    Istanbul, Istanbul, 34899, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.