Spice cream may fade facial bumps, small study hints
NCT ID NCT07334600
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested a cream made from andaliman fruit extract on 40 adults with seborrheic keratosis, harmless skin growths on the face. Participants applied the cream daily for 12 weeks, and researchers checked for changes in the growths using a special camera. The goal was to see if this natural cream could safely improve the appearance of these bumps.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- 1% andaliman fruit extract cream
- What this could lead to
- If it works, this could offer a natural, non-prescription cream to reduce the appearance of harmless skin growths on the face.
- What could go wrong
- This was a very small, single-group study with no placebo comparison, so results may not be reliable. The cream may not work for everyone, and side effects are possible.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
40 people
The number who actually took part.
- Started
-
Jan 2025
- Finished
-
Apr 2025
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 50 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients aged 18-50 years. * Patients diagnosed with common seborrheic keratosis lesions located on the facial region. * Diagnosis confirmed by clinical and dermoscopic examination. * Willing to participate in the study and provide written informed consent. Exclusion Criteria: * Pregnant or breastfeeding women. * Use of topical treatments such as 5-fluorouracil, tretinoin, adapalene, glycolic acid, alpha-hydroxy acid, or antioxidants prior to enrollment. * History of chemical peeling or laser therapy before enrollment. * Use of oral or injectable antioxidants before or during the study period. * Non-compliance with study procedures or use of additional therapies during the study period.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Seborrheic keratosis are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Outpatient Clinic, Prof. Dr. Chairuddin Panusunan Lubis Universitas Sumatera Utara Hospital
Medan, North Sumatra, 20154, Indonesia