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Simple guideline changes may cut deadly leak risk after colon surgery

NCT ID NCT07092631

Knowledge-focused Sponsor: Elie Bitar Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at 119 patients who had colon or rectal cancer surgery at a hospital in Damascus, Syria. The goal was to find out what raises the risk of a dangerous leak where the intestine is reconnected. Researchers then updated hospital guidelines to address those risks, especially low protein levels, and checked if the new guidelines helped. The study suggests that simple, low-cost changes can lower the chance of leaks and deaths after surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could lead to better surgical guidelines for low-resource settings, reducing serious complications after colorectal cancer surgery.
What could go wrong
This is a retrospective study, not a controlled trial, so it cannot prove cause and effect. Results may not apply to other hospitals or countries.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

119 people

The number who actually took part.

Started

Jan 2016

Finished

Oct 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

from the General Surgery Department of Damascus hospital, Damascus, Syria.

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients who underwent colorectal cancer surgery for tumor-related indications. Exclusion Criteria: * Emergency cases * Non-tumor related colorectal surgeries

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Conditions

The condition(s) this trial relates to.

colorectal adenocarcinoma colorectal neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anastomotic leak large intestine Anastomotic leak rectum Anastomotic leakage in colon surgery

Contacts and locations

Locations

  • Syrian Private University

    Damascus, Syria

More trials for these conditions

Other studies related to the condition(s) this trial covers.