New combo therapy aims to wipe out lingering leukemia cells in older patients
NCT ID NCT04284787
Summary
This study is for older adults newly diagnosed with a type of blood cancer called acute myeloid leukemia (AML) who cannot or choose not to have intensive chemotherapy. It compares two treatment plans: the current standard two-drug combination versus adding a third immunotherapy drug (pembrolizumab). The goal is to see if the three-drug combination helps patients achieve a deeper, longer-lasting remission by helping the immune system attack the cancer.
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Contacts and locations
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Locations
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Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center
Lebanon, New Hampshire, 03756, United States
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HaysMed
Hays, Kansas, 67601, United States
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Johns Hopkins University/Sidney Kimmel Cancer Center
Baltimore, Maryland, 21287, United States
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Lawrence Memorial Hospital
Lawrence, Kansas, 66044, United States
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MedStar Georgetown University Hospital
Washington D.C., District of Columbia, 20007, United States
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Mercy Hospital Pittsburg
Pittsburg, Kansas, 66762, United States
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Northwestern University
Chicago, Illinois, 60611, United States
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Salina Regional Health Center
Salina, Kansas, 67401, United States
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Siteman Cancer Center at Christian Hospital
St Louis, Missouri, 63136, United States
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Siteman Cancer Center at Saint Peters Hospital
City of Saint Peters, Missouri, 63376, United States
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Siteman Cancer Center at West County Hospital
Creve Coeur, Missouri, 63141, United States
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Siteman Cancer Center-South County
St Louis, Missouri, 63129, United States
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Smilow Cancer Hospital Care Center at Greenwich
Greenwich, Connecticut, 06830, United States
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Smilow Cancer Hospital Care Center at Saint Francis
Hartford, Connecticut, 06105, United States
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The University of Kansas Cancer Center - Olathe
Olathe, Kansas, 66061, United States
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University Health Truman Medical Center
Kansas City, Missouri, 64108, United States
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University of Kansas Cancer Center
Kansas City, Kansas, 66160, United States
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University of Kansas Cancer Center - Lee's Summit
Lee's Summit, Missouri, 64064, United States
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University of Kansas Cancer Center - North
Kansas City, Missouri, 64154, United States
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University of Kansas Cancer Center at North Kansas City Hospital
North Kansas City, Missouri, 64116, United States
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University of Kansas Cancer Center-Overland Park
Overland Park, Kansas, 66210, United States
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University of Kansas Health System Saint Francis Campus
Topeka, Kansas, 66606, United States
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University of Kansas Hospital-Westwood Cancer Center
Westwood, Kansas, 66205, United States
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University of Oklahoma Health Sciences Center
Oklahoma City, Oklahoma, 73104, United States
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Wake Forest Baptist Health - Wilkes Medical Center
Wilkesboro, North Carolina, 28659, United States
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Wake Forest University Health Sciences
Winston-Salem, North Carolina, 27157, United States
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Wake Forest University at Clemmons
Clemmons, North Carolina, 27012, United States
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Washington University School of Medicine
St Louis, Missouri, 63110, United States
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Yale University
New Haven, Connecticut, 06520, United States
Conditions
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