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Early cancer drug trial halted after just 3 patients

NCT ID NCT05317078

First seen Nov 01, 2025 · Last updated Jun 17, 2026 · Updated 33 times

Summary

This early-stage study tested a new drug called AMG 794 in adults with advanced lung, ovarian, or other solid tumors that have a specific protein (claudin 6). The main goals were to check safety and find the right dose. However, the study was stopped early after only 3 people enrolled, so no clear results are available.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Cabrini Hospital

    Malvern, Victoria, 3144, Australia

  • City of Hope National Medical Center

    Duarte, California, 91010, United States

  • Inselspital Bern

    Bern, 3010, Switzerland

  • Monash Medical Centre

    Clayton, Victoria, 3168, Australia

  • Southern Oncology Clinical Research Unit

    Bedford Park, South Australia, 5042, Australia

  • University of California Irvine

    Orange, California, 92868, United States

  • University of California Los Angeles

    Los Angeles, California, 90095-1678, United States

  • Virginia Commonwealth University

    Richmond, Virginia, 23219, United States

Conditions

The condition(s) this trial relates to.

Carcinoma, Ovarian Epithelial endometrial cancer malignant testicular germ cell tumor non-small cell lung carcinoma ovarian carcinoma triple-negative breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.