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New targeted drug shows promise for chinese patients with Hard-to-Treat cancers

NCT ID NCT04380753

First seen Mar 26, 2026 · Last updated May 22, 2026 · Updated 6 times

Summary

This early-phase study tested a drug called sotorasib (AMG 510) in 12 people of Chinese descent with advanced solid tumors that have a specific KRAS G12C mutation. The main goals were to check safety and how the drug moves through the body. While the drug aims to shrink tumors, this trial focused on finding the right dose and watching for side effects.

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Contacts and locations

Locations

  • National Taiwan University Hospital

    Taipei, 10002, Taiwan

  • Prince of Wales Hospital

    Shatin, New Territories, Hong Kong

  • University of Hong Kong, Queen Mary Hospital

    Hong Kong, Hong Kong

  • Veterans General Hospital - Taichung

    Taichung, 40705, Taiwan

Conditions

Explore the condition pages connected to this study.