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New drug AMG 305 tested in patients with advanced cancers

NCT ID NCT05800964

First seen Nov 01, 2025 · Last updated May 22, 2026 · Updated 26 times

Summary

This early-phase study tested a new drug, AMG 305, in 37 adults with advanced solid tumors who had no other treatment options. The main goals were to check the drug's safety and find the best dose for future studies. Researchers monitored side effects and how the drug moved through the body.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Asan Medical Center

    Seoul, 05505, South Korea

  • Beatson West of Scotland Cancer Centre

    Glasgow, G12 0YN, United Kingdom

  • Chris OBrien Lifehouse

    Camperdown, New South Wales, 2050, Australia

  • Christie Hospital

    Manchester, M20 4BX, United Kingdom

  • City of Hope National Medical Center

    Duarte, California, 91010, United States

  • Freeman Hospital

    Newcastle, NE7 7DN, United Kingdom

  • Gustave Roussy

    Villejuif, 94805, France

  • Hackensack University Medical Center

    Hackensack, New Jersey, 07601, United States

  • Hospital Clinic i Provincial de Barcelona

    Barcelona, Catalonia, 08036, Spain

  • Hospital Universitari Vall d Hebron

    Barcelona, Catalonia, 08035, Spain

  • Hospital Universitario 12 de Octubre

    Madrid, 28041, Spain

  • Hospital Universitario Madrid Sanchinarro

    Madrid, 28050, Spain

  • Institut Universitaire du Cancer Toulouse Oncopole

    Toulouse, 31059, France

  • National Cancer Center Hospital East

    Kashiwa-shi, Chiba, 277-8577, Japan

  • New York University Cancer Institute

    New York, New York, 10016, United States

  • Next Oncology

    San Antonio, Texas, 78229, United States

  • Peter MacCallum Cancer Centre

    Melbourne, Victoria, 3000, Australia

  • Princess Margaret Cancer Centre

    Toronto, Ontario, M5G 2C1, Canada

  • Royal Marsden Hospital

    Sutton, SM2 5PT, United Kingdom

  • Sarah Cannon Research Institute

    Nashville, Tennessee, 37203, United States

  • Sarah Cannon Research Institute UK

    London, W1G 6AD, United Kingdom

  • Seoul National University Hospital

    Seoul, 03080, South Korea

  • Thomas Jefferson University

    Philadelphia, Pennsylvania, 19107, United States

  • Universitaetsklinikum Dresden

    Dresden, 01307, Germany

  • Universitaetsklinikum Essen

    Essen, 45147, Germany

  • Universitaetsklinikum Wuerzburg

    Würzburg, 97078, Germany

  • University College London Hospital

    London, W1T 7HA, United Kingdom

Conditions

Explore the condition pages connected to this study.