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New vaccine aims to halt Alzheimer's brain tangles

NCT ID NCT07167966

First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 31 times

Summary

This study tests a treatment called AADvac1, which targets tau protein tangles in the brain, a hallmark of Alzheimer's. It will be given alone or with another drug (donanemab) to 450 adults aged 50-80 with early-stage Alzheimer's. The goal is to see if it safely reduces tau buildup and slows disease progression.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

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Conditions

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