Blood clot boost: could your own blood save your jawbone?
NCT ID NCT07530471
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a special blood product made from a patient's own blood can help preserve the jawbone after a tooth is pulled. After extraction, the bone and gums often shrink, which can complicate future dental implants. The treatment uses two forms of platelet-rich fibrin (T-PRF and i-PRF) placed into the extraction socket to support healing. Forty healthy adults who need a single tooth pulled will be followed for 6 months to see if this approach reduces bone loss.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- autologous platelet-rich fibrin (T-PRF and i-PRF)
- What this could lead to
- If it works, this could lead to a simple, natural way to preserve jawbone after tooth extraction, making future dental implants easier and more successful.
- What could go wrong
- This is a small, early-stage study with only 40 people, so results may not apply to everyone. Risks include pain, bleeding, and infection, though these are manageable.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 40 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Apr 2026
- Expected to finish
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Jan 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Systemically healthy individuals with no medical conditions that could interfere with periodontal treatment, tooth extraction, or wound healing * Absence of systemic diseases affecting blood coagulation and no use of anticoagulant medications * No history of blood-borne infectious diseases * Non-smokers * Age ≥18 years * Patients requiring extraction of a single-rooted tooth in the maxilla or mandible * Availability of a pre-existing CBCT scan of the planned extraction site * Extraction site suitable for implant placement Exclusion Criteria: * Presence of systemic diseases that may affect periodontal treatment, tooth extraction, wound healing, or increase the risk of complications * Presence of bleeding or coagulation disorders, or use of anticoagulant therapy * Presence of blood-borne infectious diseases * Smoking habit * Age \<18 years * Psychological or mental conditions that may affect compliance with treatment or study participation * Extraction sites not suitable for implant placement * History of previous surgical intervention or compromised healing in the extraction site * Pregnancy
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Genom att skicka in godkänner du våra Användarvillkor
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Çanakkale Onsekiz Mart University
Çanakkale, Turkey (Türkiye)
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