Can a pill beat sleepiness? new study puts alpha brain to the test
NCT ID NCT07495592
First seen Jun 27, 2026 · Last updated Jul 09, 2026 · Updated 2 times
Summary
This study looks at whether a supplement called Alpha Brain can help healthy adults think more clearly, stay alert, and feel better when they haven't had enough sleep. About 34 people will take the supplement or a placebo in random order, with no one knowing which they got. The goal is to see if it improves reaction time and reduces fatigue during a short period of sleep deprivation.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
32 people
The number who actually took part.
- Started
-
May 2026
- Finished
-
Jun 2026
- Lead sponsor
-
A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
20 to 59 years
- Sex
-
Anyone
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Healthy males and females aged 20-59 * Free of chronic diseases. * Able to read and write in English * Willing to maintain a habitual diet, supplement routine, and avoid other lifestyle changes during the study period * Willingness to meet all study requirements and restrictions. Including willing to arrive in lab in a sleep deprived state (\< or =5 hours), willing to avoid alcohol consumption 72 hours prior to testing days, and willing to avoid caffeine within 12 hours prior to testing days. Exclusion Criteria: * Habitual high caffeine consumers (\> 400 mg/day) assessed through caffeine assessment tool (Caffeine Consumption Questionnaire, CCQ) * Unwilling to wear sleep monitor at night * Known diagnosis of any cognitive impairment, cardiovascular, metabolic, endocrine, or renal disease * Has fever, or cold like symptoms * History of anxiety disorders * History of sleep disorders (i.e., insomnia), and habitually short sleepers (\<5 hours of sleep nightly) * History or current malignancy * Previous gastrointestinal surgery within the past 12 months * No alcohol consumption 72 hours prior to the start of the study/consumption of the study product and during the testing days * No caffeine consumption within 12 hours prior to the start of the study and during the testing days * Sleep medicines, melatonin, or marijuana within 1 week of the start of the study * Regular smoker * Regular drinker (\>14 drinks per week) * Current use (within the past 4 weeks) of dietary supplements or prescription medicines that may enhance cognitive performance (including, but not limited to L-Theanine, Cat's claw bark extract, Alpha GPC, Toothed clubmoss extract (Huperzine A), Bacopa, Phosphatidylserine, Paraxanthine, Pterostilbene, and Sceletium tortuosum). * Current use of prescription medications that may influence cognition (hormone therapies, peptides, etc.) * Travel involving time zone change, shift work, or other life events that alter sleep schedule \>3 hours from the norm one week before the start of the study * Any subject with a condition deemed by the investigator or sponsor to potentially interfere with study participation * Women who have been pregnant within the past 6-months, are breastfeeding, lactating, or presently planning to become pregnant during the duration of the study
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Cognitive are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Applied Science Performance Institute
Tampa, Florida, 33634, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Scientists put sleep loss under the brain scanner
- Brain zaps aimed at two networks may sharpen thinking in schizophrenia
- Exercise as a potential remedy for IBD-related fatigue
- Can a daily supplement beat fatigue? a 650-Person trial puts it to the test
- Could neck adjustments relieve Cancer-Related fatigue?
- Aromatherapy for better sleep: a natural blend put to the test