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New study aims to unlock clues about rare genetic lung disease

NCT ID NCT05297812

First seen Jan 18, 2026 · Last updated May 23, 2026 · Updated 14 times

Summary

This study follows 286 adults with Alpha-1 Antitrypsin Deficiency, a genetic condition that can damage the lungs and liver. Researchers use CT scans and blood tests to track how lung density changes over three years. The goal is to find better ways to measure disease progression, which could help design future treatments.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Boston University

    Boston, Massachusetts, 02118, United States

  • Columbia University

    New York, New York, 10032, United States

  • Medical University of South Carolina

    Charleston, South Carolina, 29425, United States

  • National Jewish Health

    Denver, Colorado, 80206, United States

  • University of Alabama at Birmingham

    Birmingham, Alabama, 35233, United States

  • University of California - Los Angeles

    Los Angeles, California, 90095, United States

  • University of Chicago

    Chicago, Illinois, 60637, United States

  • University of North Carolina

    Chapel Hill, North Carolina, 27514, United States

  • University of Utah

    Salt Lake City, Utah, 84108, United States

Conditions

Explore the condition pages connected to this study.