Hair loss gene clue found?
NCT ID NCT07455708
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether a specific gene (NR3C1) that helps control inflammation is linked to alopecia areata, an autoimmune condition that causes hair loss. Researchers compared 120 people with and without the condition to see if gene variations affect disease risk or severity. The goal was to better understand the biology behind the disease, not to test a new treatment.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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120 people
The number who actually took part.
- Started
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Nov 2023
- Finished
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Dec 2024
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The study will include 60 patients clinically diagnosed with alopecia areata and 60 age- and sex-matched healthy controls recruited from the same geographic area.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria (Cases): * Clinically diagnosed alopecia areata * Age ≥ 18 years * Both sexes * Willingness to participate and provide informed consent Inclusion Criteria (Controls): * Apparently healthy individuals * No history of autoimmune disease * Age- and sex-matched to cases * Provided informed consent Exclusion Criteria: * Presence of other autoimmune or inflammatory diseases * Current systemic immunosuppressive therapy * Pregnancy or lactation * Refusal to participate
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Benha University
Banhā, Qalyubia Governorate, 13511, Egypt
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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