Major trial aims to Fine-Tune leukemia treatment for thousands

NCT ID NCT04307576

Recruiting now Disease control Sponsor: Mats Heyman Source: ClinicalTrials.gov ↗

Summary

This large European study aims to improve survival and reduce side effects for children and young adults (ages 0-45) newly diagnosed with acute lymphoblastic leukemia (ALL). It will test whether treatment can be safely reduced for some patients and whether adding newer drugs can prevent relapse for others. The goal is to find the right balance of therapy to control the cancer while minimizing long-term health risks.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Aalborg University Hospital, Dept of Paediatrics
RECRUITING

Aalborg, 9000, Denmark

Contact
Aarhus University Hospital
RECRUITING

Aarhus, 8000, Denmark

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Aarhus University Hospital, Child and Adolescent Health
RECRUITING

Aarhus, 8200, Denmark

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Aberdeen Royal Infirmary, Aberdeen
NOT_YET_RECRUITING

Aberdeen, AB25 2ZN, United Kingdom

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Addenbrooke's Hospital, Cambridge
RECRUITING

Cambridge, CB2 0QQ, United Kingdom

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Alder Hey Children's Hospital, Liverpool
RECRUITING

Liverpool, L12 2AP, United Kingdom

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Beatson West of Scotland Cancer Centre, Glasgow
NOT_YET_RECRUITING

Glasgow, G12 0YN, United Kingdom

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Belfast City Hospital, Belfast
NOT_YET_RECRUITING

Belfast, BT9 7AB, United Kingdom

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Birmingham Children's Hospital, Birmingham
RECRUITING

Birmingham, B4 6NH, United Kingdom

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Bristol Royal Hospital for Children / Bristol Haematology and Oncology Centre
RECRUITING

Bristol, BS2 8BJ, United Kingdom

Contact

Contact
CHC MontLégia, Boulevard Patience et Beaujonc 2
RECRUITING

Liège, 4000, Belgium

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CHR de la Citadelle
RECRUITING

Liège, 4000, Belgium

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CHRU Besançon
RECRUITING

Besançon, 25030, France

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CHRU Brest - Morvan
RECRUITING

Brest, 29609, France

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CHRU Tours- Hôpital Clocheville
RECRUITING

Tours, 37000, France

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CHRU de Lille - Hôpital Jeanne de Flandre
RECRUITING

Lille, 59037, France

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CHU Amiens Groupe Hospitalier Sud
RECRUITING

Amiens, 80054, France

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CHU Angers
RECRUITING

Angers, 49033, France

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CHU Bordeaux - Groupe Hospitalier Pellegrin
RECRUITING

Bordeaux, 33076, France

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CHU Clermont-Ferrand
RECRUITING

Clermont-Ferrand, 63000, France

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CHU De La Réunion - Site Nord (Hôpital Félix GUYON)
RECRUITING

Saint-Denis, 97400, France

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CHU Dijon Hôpital François Mitterrand
RECRUITING

Dijon, 21000, France

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CHU Nantes-Hôpital enfant-adolescent
RECRUITING

Nantes, 44093, France

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CHU Nice - Hôpital l'Archet 2
RECRUITING

Nice, 6200, France

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CHU Paris - Hôpital Robert Debré
RECRUITING

Paris, 75019, France

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CHU Paris Armand Trousseau
RECRUITING

Paris, 75012, France

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CHU Paris Saint Louis
RECRUITING

Paris, 75010, France

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CHU Poitiers
RECRUITING

Poitiers, 86021, France

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CHU Reims-American Hospital
RECRUITING

Reims, 51100, France

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CHU Rennes - Hôpital sud
RECRUITING

Rennes, 35203, France

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CHU Rouen
RECRUITING

Rouen, 76031, France

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CHU Saint Etienne Hôpital Nord
RECRUITING

Saint-Etienne, 42055, France

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CHU Strasbourg -Hôpital de Hautepierre
RECRUITING

Strasbourg, 67098, France

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CHU Toulouse
RECRUITING

Toulouse, 31059, France

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CHU de Grenoble site Nord - Hôpital Albert Michallon
RECRUITING

Grenoble, 38043, France

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CHU de Lyon HCL - GH Est-Institut d'hématologie et d'oncologie pédiatrique IHOP
RECRUITING

Lyon, 69373, France

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CHU de Marseille - Hôpital de la Timone
RECRUITING

Marseille, 13385, France

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CHU de Montpellier - Hôpital Arnaud de Villeneuve
RECRUITING

Montpellier, 34295, France

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CHU de Nancy - Hôpital de Brabois Enfant
RECRUITING

Vandœuvre-lès-Nancy, 54511, France

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Centre Hospitalier Universitaire Caen
RECRUITING

Caen, 14033, France

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Centro Hospitalar e Universitário de Coimbra, EPE - Hospital Pediátrico de Coimbra
NOT_YET_RECRUITING

Coimbra, 3000-602, Portugal

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Children's Hospital, Affiliate of Vilnius University Hospital Santaros Klinikos
RECRUITING

Vilnius, 08661, Lithuania

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Churchill Hospital, Oxford
NOT_YET_RECRUITING

Oxford, OX3 7LE, United Kingdom

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Cliniques Universitaires Saint-Luc (UCL)
RECRUITING

Brussels, 1200, Belgium

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Derriford Hospital
RECRUITING

Plymouth, United Kingdom

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Evangelisches Klinikum Bethel
RECRUITING

Bielefeld, 33617, Germany

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Freeman Hospital, Newcastle
NOT_YET_RECRUITING

Newcastle, NE7 7DN, United Kingdom

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Great Ormond Street Hospital for Children, London
RECRUITING

London, WC1N 3JH, United Kingdom

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HELIOS Klinikum Krefeld
RECRUITING

Krefeld, 47805, Germany

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Haukeland University Hospital, Dept of Haematology
RECRUITING

Bergen, 5021, Norway

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Haukeland University Hospital, Dept of Paediatrics
RECRUITING

Bergen, 5021, Norway

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Helsinki University Hospital, Dept of Haematology
RECRUITING

Helsinki, 00029, Finland

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Helsinki University Hospital, Dept of Paediatrics
RECRUITING

Helsinki, 00029, Finland

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Hospital Infantil Universitario Nino Jesus
NOT_YET_RECRUITING

Madrid, Spain

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Hospital Sant Joan De Deu Barcelona
NOT_YET_RECRUITING

Esplugues de Llobregat, Spain

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Hospital Universitari Vall D Hebron
NOT_YET_RECRUITING

Barcelona, Spain

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Hospital Universitario De Cruces
NOT_YET_RECRUITING

Barakaldo, Spain

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Hospital Universitario La Paz
NOT_YET_RECRUITING

Madrid, Spain

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Hospital Universitario Miguel Servet
NOT_YET_RECRUITING

Zaragoza, Spain

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Hospital Universitario Y Politecnico La Fe
NOT_YET_RECRUITING

Valencia, Spain

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Hôpital de la mère et de l'enfant
RECRUITING

Limoges, 87042, France

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Instituto Português de Oncologia de Lisboa Francisco Gentil, EPE
RECRUITING

Lisbon, 1099-023, Portugal

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Instituto Português de Oncologia do Porto Francisco Gentil, EPE
RECRUITING

Porto, 4200-072, Portugal

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John Radcliffe Hospital, Oxford
RECRUITING

Oxford, OX3 9DU, United Kingdom

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Karolinska University Hospital, Dept of Paediatric Oncology and Haematology
RECRUITING

Stockholm, 17176, Sweden

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Karolinska University Hospital, Patient area Haematology
RECRUITING

Stockholm, 17176, Sweden

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King's College Hospital
RECRUITING

London, United Kingdom

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Klinikum Bremen Mitte
RECRUITING

Bremen, 28177, Germany

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Kuopio University Hospital, Dept of Haematology
RECRUITING

Kuopio, 70029, Finland

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Kuopio University Hospital, Dept of Paediatrics
RECRUITING

Kuopio, 70029, Finland

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L'hôpital Universitaire des enfants Reine Fabiola (Huderf)
RECRUITING

Brussels, 1020, Belgium

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Landspitali University Hospital, Children's Hospital
RECRUITING

Reykjavik, 101, Iceland

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Leeds General Infirmary, Leeds
RECRUITING

Leeds, LS1 3EX, United Kingdom

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Leeds St James University Hospital
RECRUITING

Leeds, LS9 7TF, United Kingdom

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Leicester Royal Infirmary, Leicester
RECRUITING

Leicester, LE1 5WW, United Kingdom

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Linköping University Hospital, Dept of Haematology
RECRUITING

Linköping, 58185, Sweden

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Linköping University Hospital, Dept of Paediatrics
RECRUITING

Linköping, 58185, Sweden

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Ninewells Hospital, Dundee
NOT_YET_RECRUITING

Dundee, DD1 9SY, United Kingdom

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Noah's Ark Children's Hospital for Wales, Cardiff
NOT_YET_RECRUITING

Cardiff, CF14 4XW, United Kingdom

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Norrland University Hospital, Dept of Haematology
RECRUITING

Umeå, 90185, Sweden

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Norrland University Hospital, Dept of Paediatrics
RECRUITING

Umeå, 90185, Sweden

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North Estonia Medical Centre, Dept of Haematology
RECRUITING

Tallinn, 13419, Estonia

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Nottingham City Hospital
NOT_YET_RECRUITING

Nottingham, NG5 1PB, United Kingdom

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Nottingham Queen's Medical Centre
RECRUITING

Nottingham, NG7 2UH, United Kingdom

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Odense University Hospital, Dept of Paediatrics
RECRUITING

Odense, 5000, Denmark

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Oslo University Hospital, Dept of Haematology
RECRUITING

Oslo, 0372, Norway

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Oslo University Hospital, Dept of paediatric haemato- and oncology
RECRUITING

Oslo, 0424, Norway

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Oulu University Hospital, Dept of Haematology, Dept of Medicine
RECRUITING

Oulu, 90029, Finland

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Oulu University Hospital, Dept of Paediatrics
RECRUITING

Oulu, 90029, Finland

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Our Lady's Children's Hospital
RECRUITING

Dublin, Ireland

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Princess Máxima Center for Pediatric Oncology
RECRUITING

Utrecht, 3584, Netherlands

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Rigshospitalet, Dept of Haematology
RECRUITING

Copenhagen, 2100, Denmark

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Rigshospitalet, Dept of Paediatrics
RECRUITING

Copenhagen, 2100, Denmark

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Royal Aberdeen Children's Hospital, Aberdeen
RECRUITING

Aberdeen, United Kingdom

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Royal Belfast Hospital for Sick Children, Belfast
NOT_YET_RECRUITING

Belfast, BT12 6BA, United Kingdom

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Royal Hallamshire Hospital, Sheffield
RECRUITING

Sheffield, S10 2JF, United Kingdom

Contact
Royal Hospital for Children and Young People, Edinburgh
RECRUITING

Edinburgh, EH9 1LF, United Kingdom

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Royal Hospital for Children, Glasgow
RECRUITING

Glasgow, G51 4TF, United Kingdom

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Royal Manchester Children's Hospital, Manchester
RECRUITING

Manchester, M13 9WL, United Kingdom

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Royal Marsden Hospital, Sutton
RECRUITING

Sutton, SM2 5PT, United Kingdom

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Royal Stoke University Hospital, Stoke
NOT_YET_RECRUITING

Stoke, ST4 6QG, United Kingdom

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Royal Victoria Infirmary, Newcastle
RECRUITING

Newcastle upon Tyne, NE1 4LP, United Kingdom

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Sahlgrenska University Hospital, Dept of Paediatric Haematology and Oncology
RECRUITING

Gothenburg, 41685, Sweden

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Sahlgrenska University Hospital, Section for Haematology and coagulation
RECRUITING

Gothenburg, 41345, Sweden

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Sheffield Children's Hospital, Sheffield
RECRUITING

Sheffield, S10 2TH, United Kingdom

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Skåne University Hospital, Dept of Haematology
RECRUITING

Lund, 22185, Sweden

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Skåne University Hospital, Dept of Paediatrics
RECRUITING

Lund, 22185, Sweden

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Southampton General Hospital, Southampton
RECRUITING

Southampton, SO16 6YD, United Kingdom

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St. Bartholomews Hospital
RECRUITING

London, United Kingdom

Contact
St. Olavs University Hospital, Dept of Haematology
RECRUITING

Trondheim, 7030, Norway

Contact
St. Olavs University Hospital, Dept of Paediatrics
RECRUITING

Trondheim, 7006, Norway

Contact
Stavanger University Hospital, Dept of Haematology
RECRUITING

Stavanger, 4011, Norway

Contact
Tallinn Children´s Hospital, Dept of Paediatrics
RECRUITING

Tallinn, 13419, Estonia

Contact
Tampere University Hospital, Dept of Haematology
RECRUITING

Tampere, 33521, Finland

Contact
Tampere University Hospital, Dept of Paediatrics
RECRUITING

Tampere, 33521, Finland

Contact
Tartu University Hospital
RECRUITING

Tartu, 50406, Estonia

Contact
The Christie NHS Foundation Trust (PTC)
RECRUITING

Manchester, M20 4BX, United Kingdom

Contact
The Clatterbridge Cancer Centre NHS Foundation Trust
RECRUITING

Liverpool, United Kingdom

Contact
The Queen Elizabeth Hospital, Birmingham
RECRUITING

Birmingham, B15 2TH, United Kingdom

Contact
Turku University Hospital, Clinical Haematology and Stem Cell Transplantation Unit
RECRUITING

Turku, 20520, Finland

Contact
Turku University Hospital, Dept of Paediatrics
RECRUITING

Turku, 20520, Finland

Contact
University College London Hospital, London
RECRUITING

London, NW1 2BU, United Kingdom

Contact
University Hospital Antwerp
RECRUITING

Edegem, 2650, Belgium

Contact
University Hospital Ghent
RECRUITING

Ghent, 9000, Belgium

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University Hospital Leuven, Dept of Paediatrics
RECRUITING

Leuven, 3000, Belgium

Contact
University Hospital North Norway, Dept of Haematology
RECRUITING

Tromsø, 9019, Norway

Contact
University Hospital Son Espases
NOT_YET_RECRUITING

Palma de Mallorca, Spain

Contact
University Hospital Virgen Del Rocio S.L.
NOT_YET_RECRUITING

Seville, Spain

Contact
University Hospital of North Norway, Dept of Paediatrics
RECRUITING

Tromsø, 9038, Norway

Contact
University Hospital of Wales, Cardiff
NOT_YET_RECRUITING

Cardiff, United Kingdom

Contact
University Medical Center Utrecht
RECRUITING

Utrecht, Netherlands

Contact
Universitätsklinikum Bonn
RECRUITING

Bonn, 53113, Germany

Contact
Universitätsklinikum Hamburg-Eppendorf
RECRUITING

Hamburg, 20246, Germany

Contact
Universitätsmedizin Mainz
RECRUITING

Mainz, 55131, Germany

Contact
Uppsala University Hospital, Dept of Haematology
RECRUITING

Uppsala, 75185, Sweden

Contact
Uppsala University Hospital, Dept of Paediatric Haematology and Oncology
RECRUITING

Uppsala, 75185, Sweden

Contact
Vilnius University Hospital Santaros Klinikos
NOT_YET_RECRUITING

Vilnius, 08661, Lithuania

Contact
Western General Hospital, Edinburgh
RECRUITING

Edinburgh, EH2 2XU, United Kingdom

Contact
Örebro University Hospital, Section for Haematology
RECRUITING

Örebro, 70185, Sweden

Contact

Conditions

Explore the condition pages connected to this study.

LEUKEMIA, ACUTE LYMPHOBLASTIC