New drug ALE.P02 targets tough cancers in early trial
NCT ID NCT06747585
First seen Nov 01, 2025 · Last updated Apr 29, 2026 · Updated 25 times
Summary
This study tests a new drug, ALE.P02, designed to find and attack cancer cells that have a specific protein called Claudin-1. It is for adults with advanced or spreading squamous cell cancers of the lung, head and neck, cervix, or esophagus who have already tried standard treatments. The main goals are to check the drug's safety, find the best dose, and see if it can shrink tumors.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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AP-HM Hôpital de La Timone CEPCM
RECRUITINGMarseille, 13005, France
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Buddihist Tzu Chi Medical Foundation - Taipei Tzu Chi Hospital
RECRUITINGTaipei, 231020, Taiwan
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CHRU De Lille- Hôpital Claude Huriez - Medical Oncology
RECRUITINGLille, 59000, France
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Centre Georges Francois Leclerc - Oncologie Medicale
RECRUITINGDijon, 21079, France
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Centre Hospitalier Universitaire (CHU) de Toulouse - IUCT Oncopole
RECRUITINGToulouse, 31100, France
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Centro Ricerche Cliniche Verona
RECRUITINGVerona, Italy
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Changhua Christian Medical Foundation Changhua Christian Hospital
RECRUITINGChanghua, 50006, Taiwan
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Changhua Christian Medical Foundation Changhua Christian Hospital
RECRUITINGChanghua, 500209, Taiwan
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Chinese University of Hong Kong - Prince of Wales Hospital
RECRUITINGShatin, N.T., Hong Kong
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Hackensack University Medical Center
RECRUITINGHackensack, New Jersey, 07601, United States
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Hospital Universitari Vall D Hebron
RECRUITINGBarcelona, 08035, Spain
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Hospital Universitario 12 de Octubre
RECRUITINGMadrid, 28041, Spain
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Hospital Universitario Quironsalud Madrid
RECRUITINGPozuelo de Alarcón, Madrid, 28223, Spain
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Hospital Universitario Virgen De La Macarena
RECRUITINGSeville, 41009, Spain
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Hospital Universitario Virgen De La Victoria
RECRUITINGMálaga, 29010, Spain
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Hospital Universitario Y Politécnico La Fe
RECRUITINGValencia, 46026, Spain
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IEO - Istituto Europeo di Oncologia, IRCCS
RECRUITINGMilan, 20141, Italy
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Institut Bergonie
RECRUITINGBordeaux, 33000, France
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Institut Gustave Roussy
RECRUITINGVillejuif, 94800, France
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Mayo Foundation for Medical Education and Research - Mayo Cl
RECRUITINGScottsdale, Arizona, 85259, United States
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NEXT Oncology Barcelona
RECRUITINGBarcelona, 08023, Spain
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NEXT Oncology Virginia
RECRUITINGFairfax, Virginia, 22031, United States
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National Cancer Center
RECRUITINGGoyang-si, 10408, South Korea
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National Cancer Centre Singapore
RECRUITINGSingapore, South West, 168583, Singapore
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National Taiwan University Hospital
RECRUITINGTaipei, 100225, Taiwan
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National University Cancer Institue
RECRUITINGSingapore, South West, 11907, Singapore
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Norton Cancer Institue Downtown
RECRUITINGLouisville, Kentucky, 40202, United States
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Ospedale San Raffaele, IRCCS
RECRUITINGMilan, 20132, Italy
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Ospedale Santa Maria delle Croci di Ravenna Oncologia
RECRUITINGRavenna, 48121, Italy
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PU A. Gemelli, Universita Cattolica del Sacro Cuore
RECRUITINGRoma, Italy
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Providence Medical Foundation
RECRUITINGFullerton, California, 92835, United States
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START Hospital HM Nou Delfos
RECRUITINGBarcelona, Spain
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START Madrid- Centro Integral Oncologico Clara Campal
RECRUITINGPAU de Sanchinarro, Madrid, 28050, Spain
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Seoul National University Hospital
RECRUITINGSeoul, 03080, South Korea
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Severance Hospital, Yonsei University Health System
RECRUITINGSeoul, 03722, South Korea
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The University of Chicago Medical Center - Oncology
RECRUITINGChicago, Illinois, 60637, United States
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USC Norris Comprehensive Cancer Center
RECRUITINGLos Angeles, California, 90033, United States
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Yale Comprehensive Cancer Center
RECRUITINGNew Haven, Connecticut, 06510, United States
Conditions
Explore the condition pages connected to this study.