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New combo therapy shows promise in stomach cancer battle

NCT ID NCT05008783

First seen Nov 19, 2025 · Last updated May 23, 2026 · Updated 22 times

Summary

This study tested whether adding the drug AK104 to standard chemotherapy helps people with advanced stomach or gastroesophageal junction cancer live longer. The trial involved 610 adults and compared AK104 plus chemo to a placebo plus chemo. The main goal was to see if the combination improves overall survival.

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Contacts and locations

Locations

  • Fudan University Cancer Hospital

    Shanghai, Shanghai Municipality, 200032, China

  • Fujian Provincial Cancer Hospital

    Fuzhou, Fujian, 350014, China

  • Peking University Cancer Hospital

    Beijing, Beijing Municipality, 100143, China

  • The First Affiliated Hospital of Zhejiang University Medical College

    Hangzhou, Zhejiang, 310003, China

  • West China Hospital of Sichuan University

    Chengdu, Sichuan, 610044, China

  • Yunnan Cancer Hospital

    Kunming, Yunnan, 650118, China

  • Zhongshan Hospital, Fudan University

    Shanghai, Shanghai Municipality, 20032, China

Conditions

Explore the condition pages connected to this study.