Can AI be a second pair of eyes for liver cancer detection?
NCT ID NCT07768085
First seen Aug 17, 2026 · Last updated Aug 18, 2026 · Updated 1 time
Summary
This trial asks whether adding artificial intelligence (AI) to radiologists' reading of liver CT scans can match or improve standard reporting. It involves 40,000 adults who had contrast-enhanced CT scans of the abdomen. On some days, radiologists first read scans on their own, then see AI suggestions and may revise their reports; on other days, they use the usual workflow without AI. The main goal is to see if AI-assisted reading misses fewer clinically significant liver cancers, while also checking detection rates, diagnostic accuracy, and reporting speed.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- AI-assisted reading of contrast-enhanced CT scans
- What this could lead to
- If AI assistance proves non-inferior and improves detection, it could become a standard tool to help radiologists catch liver cancers earlier and reduce missed diagnoses.
- What could go wrong
- The trial is large but still early; AI may not consistently improve accuracy across all settings, and reliance on AI could introduce new errors or workflow issues.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
About 40,000 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
-
Aug 2026
An estimate. Start dates often move.
- Expected to finish
-
Dec 2027
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 years and older
- Sex
-
Anyone
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Age range 18 years and above 2. Underwent dynamic contrast-enhanced abdominal CT examination with liver coverage 3. Imaging must include at least three required phases: non-contrast, arterial phase, and venous phase; a delayed phase is optional 4. Complete imaging data that meet AI system and radiologist interpretation requirements. Exclusion Criteria: 1. History of recent upper-abdominal surgery (within 30 days) or major hepatobiliary-pancreatic surgery affecting liver evaluation (e.g., liver transplantation or Whipple procedure); patients with prior simple cholecystectomy or single-lesion interventional procedures are not excluded 2. History of recent hepatic trauma (within 30 days) 3. Poor image quality or severe noise artifacts (e.g., metal or motion artifacts) 4. Missing required imaging phases (required at least non-contrast, arterial, and venous phases) or inadequate scan range (e.g., lower-abdomen CT such as pelvic or rectal scans not covering the liver)
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Cyst are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The places running it
1 site. The list below names each one and where it is.
-
The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
-
Shengjing Hospital of China Medical University
Shenyang, Liaoning, 110004, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can two immunotherapy drugs make liver tumors more vulnerable to surgery?
- Two blood markers put to the test for early liver cancer detection
- Saline barrier lets heat target liver tumors near the diaphragm
- Can a new PET tracer spot liver cancer more clearly?
- Can a targeted pill shrink hard-to-treat bile duct cancers?
- Can a smart drug starve liver tumors without harming healthy tissue?