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AI and ultrasound join forces to detect hidden muscle decline in the ICU

NCT ID NCT06765551

Diagnosis Sponsor: Jena University Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 18, 2026 · Last updated Aug 19, 2026 · Updated 1 time

Summary

This study explores whether artificial intelligence can analyze ultrasound images of muscles to detect intensive care unit-acquired weakness (ICUAW), a common complication in critically ill patients. Researchers will compare AI-based assessments with standard clinical evaluations in 64 participants, including ICU patients and healthy volunteers. The goal is to see if AI can reliably identify and monitor this condition, potentially leading to earlier detection and better management.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Neuromuscular ultrasound with AI-based image analysis
What this could lead to
If successful, this could lead to a non-invasive, AI-assisted tool for early detection and monitoring of ICU-acquired weakness, potentially improving patient outcomes.
What could go wrong
This is a small observational study, so results may not be conclusive. AI accuracy may vary, and findings may not generalize to all ICU patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

64 people

The number who actually took part.

Started

Oct 2024

Finished

Jul 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

All patients with critical illness fulfilling the inclusion criteria should be screened for the study on two surgical ICUs at the department of anesthesiology and intensive care medicine of Jena University Hospital, Germany.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients aged 18 years or above * Major elective surgery, e.g. cardiothoracic or abdominal surgery * Expected ICU stay \>1 day postoperatively * Healthy, age-machted subjects without ICUAW (recruited from staff of the department of anesthesiology and intensive care medicine) Exclusion Criteria: * No informed consent * Emergency surgery * Previous participation in the same study * Preexisting neuromuscular disease * Preexisting central nervous system disease with residual neuromuscular impairment (e.g. cerebral haemorrhage, stroke, brain tumor) * High-dose glucocorticoid therapy (\>300 mg hydrocortisone or equivalent per day) before or during particiation in the study

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Conditions

The condition(s) this trial relates to.

Asthenia critical illness polyneuropathy polyneuropathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Artifical intelligence Intensive care unit-acquired weakness Ultrasound

Contacts and locations

Locations

  • Department of Anesthesiology and Intensive Care Medicine, Jena University Hospital

    Jena, Thuringia, 07747, Germany

More trials for these conditions

Other studies related to the condition(s) this trial covers.