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AI brain zaps aim to unlock paralyzed fingers in stroke survivors

NCT ID NCT07491029

Symptom relief Sponsor: NEUROPHET Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a non-invasive, AI-powered brain stimulation technique can improve finger movement in people who had a stroke within the past 3 months. About 116 adults with arm and hand paralysis will receive either real or fake (sham) stimulation to see if the real treatment leads to better motor recovery. The goal is to find a safe, effective way to help stroke survivors regain hand function.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 116 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Apr 2026

An estimate. Start dates often move.

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

19 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Participants must meet all of the following criteria to be eligible for this clinical trial: 1. Adults aged 19 years or older 2. Patients with stroke confirmed by brain imaging 3. Subacute stroke patients within 2 weeks to 3 months after stroke onset 4. Patients with unilateral upper-extremity paralysis 5. Upper-extremity Fugl-Meyer Assessment (FMA-UE, maximum score 66) score between 20 and 56 6. Participants who voluntarily provide written informed consent after receiving and understanding the study procedures and requirements Exclusion Criteria: Participants will be excluded if they meet any of the following criteria: 1. History of a condition affecting the function of the paralyzed arm 2. Inability to follow instructions or complete the study due to cognitive impairment or aphasia 3. Evidence of delirium, confusion, or other disorders of consciousness 4. Presence of uncontrolled medical or surgical conditions 5. Severe neurological disorders associated with major psychiatric conditions (e.g., major depressive disorder, schizophrenia, bipolar disorder, or dementia) 6. History of uncontrolled epilepsy (seizure disorder) 7. Contraindications to transcranial direct current stimulation (tDCS), including: * Scalp disease or metal materials at the electrode attachment site * Presence of a cardiac pacemaker or cochlear implant 8. Medical contraindications to MRI examination 9. Pregnant or breastfeeding women, or those planning pregnancy during the study period 10. Use of a stimulation device similar to the investigational device or participation in a related clinical study within the past 1 year 11. Individuals judged by the investigator to be medically or ethically unsuitable for participation in this clinical study

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Conditions

The condition(s) this trial relates to.

stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Subacute stroke Upper extremity function

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Severance Hospital

    Seoul, South Korea

More trials for these conditions

Other studies related to the condition(s) this trial covers.