AI as a second opinion: could it sharpen emergency diagnoses?
NCT ID NCT07766863
First seen Aug 17, 2026 · Last updated Aug 18, 2026 · Updated 1 time
Summary
This study tests whether a generative AI tool can improve the accuracy of differential diagnoses made by physicians in emergency departments. Researchers will compare the final diagnoses made by doctors with and without AI support, involving 500 adult patients at two hospitals. The goal is to see if AI assistance leads to more correct diagnoses and changes how doctors rank possible conditions.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- generative artificial intelligence (AI) as a diagnostic support tool
- What this could lead to
- If effective, AI could become a standard aid in emergency rooms, helping doctors consider a wider range of possible diagnoses and reduce missed or delayed diagnoses.
- What could go wrong
- The trial is relatively small and results may not apply to all settings. AI suggestions might not always be accurate or could introduce bias, and doctors may not always follow them.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 500 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jun 2026
- Expected to finish
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Jun 2029
An estimate. End dates often move.
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients admitted to the hospital via the emergency department at Karolinska University Hospital in Huddinge and Solna, Sweden.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adult patients \>18 years admitted through the emergency departments at Karolinska University Hospital in Huddinge and Solna. Exclusion Criteria: * Children \<18 years * Patients without a recorded final diagnosis
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Karolinska University Hospital
RECRUITINGStockholm, Huddinge, 14186, Sweden
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