AI-ECG could catch deadly lung condition before It's too late
NCT ID NCT07079592
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether an artificial intelligence-enhanced electrocardiogram (AI-ECG) can detect pulmonary hypertension—a serious condition where blood pressure in the lungs is dangerously high—in people aged 50 to 85 who are at risk. Over 8,600 participants will get the AI-ECG screening; those flagged as high-risk will then receive an echocardiogram to confirm the diagnosis. The goal is to see if this approach leads to earlier detection and better heart and lung outcomes.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- AI-ECG screening tool
- What this could lead to
- If successful, this AI-ECG could become a quick, low-cost way to screen for pulmonary hypertension, catching it earlier and improving outcomes.
- What could go wrong
- This is a large but early-stage validation study. The AI may not be accurate enough in real-world settings, and false positives or negatives could limit its usefulness.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 8,666 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Feb 2026
An estimate. Start dates often move.
- Expected to finish
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Jun 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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50 to 85 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Men or women, ≥ 50 to 85 years of age * At least one 12-lead ECG within 3 months Exclusion Criteria: * A diagnosis of PH WHO Groups 1, 2, 3, 4, or 5 * A diagnosis of hypertrophic cardiomyopathy, restrictive cardiomyopathy, constrictive pericarditis, cardiac amyloidosis, or infiltrative cardiomyopathy * Prior heart, lung, or heart-lung transplants * Any systolic pulmonary artery pressure \>50 mmHg by echocardiography before * Echocardiography in 3 months before index ECG
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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National Defense Medical Center
RECRUITINGTaipei, Taiwan
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