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AI and blood tests join forces to catch lung cancer sooner

NCT ID NCT05368298

Diagnosis Sponsor: University of Oxford Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study collects blood samples from 872 people with lung nodules to develop artificial intelligence (AI) tools that can help diagnose lung cancer earlier and more accurately. The goal is to combine blood tests with CT scans to improve detection and reduce the need for invasive procedures. Participants are adults with suspicious lung nodules found during screening who need further testing.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

872 people

The number who actually took part.

Started

Aug 2022

Expected to finish

Sep 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients who have been offered follow up appointments after their Lung Health Check. Patients may be invited to attend a Lung Health Check if they have ever smoked and are aged 55 - 75 years old.

Ages

55 to 75 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Patient suitability will be assessed against the below criteria by the clinical teams managing the patients. Inclusion Criteria: 1. Patients with a pulmonary nodule or nodule(s) detected on a CT scan performed as part of Lung Cancer Screening from the Lung Health Check centres, that require further investigation with a PET-CT scan, and / or biopsy, and / or resection 2. Willing and able to give informed consent Exclusion Criteria: * None -

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Conditions

The condition(s) this trial relates to.

disease lung cancer lung neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Lung cancer

Contacts and locations

Locations

  • Lung Health Check Centre: Cheshire & Merseyside

    Liverpool, United Kingdom

  • Lung Health Check Centre: Corby & Kettering

    Kettering, United Kingdom

  • Lung Health Check Centre: Gateshead

    Gateshead, United Kingdom

  • Lung Health Check Centre: Newcastle & Gateshead

    Newcastle, United Kingdom

  • Lung Health Check Centre: North Bristol

    Bristol, United Kingdom

  • Lung Health Check Centre: Plymouth

    Plymouth, United Kingdom

  • Lung Health Check Centre: RM Partners

    London, United Kingdom

  • Lung Health Check Centre: Royal Sussex

    Brighton, United Kingdom

  • Lung Health Check Centre: South Tyneside and Sunderland

    Sunderland, United Kingdom

  • Lung Health Check Centre: Stoke

    Stoke, United Kingdom

  • Lung Health Check: Oxford - Churchill Hospital, OUH

    Oxford, Oxfordshire, United Kingdom

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