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AI vs. rare diseases: can a computer Out-Diagnose doctors?

NCT ID NCT07625436

Diagnosis Sponsor: Peking Union Medical College Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether an artificial intelligence (AI) tool can help doctors better diagnose rare diseases. About 150 doctors will either use the AI or rely on standard methods to diagnose real patient cases. The goal is to see if AI improves accuracy and speed, which could lead to faster treatment for patients with hard-to-diagnose conditions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 150 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jun 2026

An estimate. Start dates often move.

Expected to finish

Jun 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * 1\. Licensed physicians at the junior or senior level affiliated with internal medicine, neurology, pediatrics, and rare disease-related departments. * 2\. Willingness to provide written informed consent, adhere to trial protocols, and complete all required pre-study training prior to enrollment. Exclusion Criteria: * 1\. Prior exposure to any of the clinical cases included in the study case library. * 2\. Direct participation in the design or development of the AI model.

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Conditions

The condition(s) this trial relates to.

disease Rare Diseases

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Rare diseases Rare disorders

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    13 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Cangzhou Central Hospital

    Cangzhou, China

  • Changchun Sacred Heart Hospital

    Changchun, China

  • Dongguan People's Hospital

    Dongguan, China

  • First People's Hospital of Foshan

    Foshan, China

  • Guizhou Provincial People's Hospital

    Guiyang, China

  • Jilin Central General Hospital

    Jilin City, China

  • Peking Union Medical College Hospital

    Beijing, China

  • Qinghai Provincial People's Hospital

    Xining, China

  • The First People's Hospital of Yunnan Province

    Kunming, China

  • Tianjin Children's Hospital

    Tianjin, China

  • Tibet Autonomous Region People's Hospital

    Lhasa, China

  • Wuhai People's Hospital

    Wuhai, China

  • Zhangzhou Municipal Hospital of Fujian Province

    Zhangzhou, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.