AI reads scans to spot hidden cancer spread
NCT ID NCT07183124
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tests an AI-powered 3D imaging model to improve detection of cancer spread in patients with stage II-III rectal cancer. Researchers will analyze existing CT and MRI scans from 1,500 patients to see if the AI can predict whether the cancer has reached the edge of the tissue removed during surgery. The goal is to help doctors plan more precise treatments.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- AI-Assisted 3D Imaging Model
- What this could lead to
- If successful, this AI tool could help doctors more accurately detect if rectal cancer has spread to nearby tissues, leading to better surgical planning and outcomes.
- What could go wrong
- This is a retrospective study using existing images, not a real-time test. The AI may not perform as well in different hospitals or with different scanners.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 1,500 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Oct 2025
An estimate. Start dates often move.
- Expected to finish
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Jul 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The study population consists of adult patients (≥18 years) diagnosed with stage II-III locally advanced rectal cancer (LARC) without distant metastasis (M0), who received care at Taichung Veterans General Hospital (TVGH), Taiwan. Eligible participants have adequate physical status (ASA I-III) to undergo standard treatment and surgery, no history of other malignancies or major diseases affecting tumor assessment within the past three years, and complete medical records including CT and MRI imaging. Patients with stage I or IV disease, insufficient physical status, major comorbidities, or incomplete imaging/medical records are excluded.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Diagnosed with rectal cancer, clinical stage II-III, with no distant metastasis (M0) * Age over 18 years, with adequate physical status classified as American Society of Anesthesiologists (ASA) I-III, capable of receiving treatment and surgery * No history of other malignancies or major diseases affecting study assessment within the past three years. * Complete medical records, including available CT and MRI imaging. Exclusion Criteria: * Patients with clinical stage I or IV rectal cancer. * Age under 18 years, or physical status not meeting American Society of Anesthesiologists (ASA) I-III criteria, unable to undergo surgery or related treatment. * Presence of other major diseases or malignancies affecting tumor assessment (e.g., diagnosis of another malignancy within the past three years, uncontrolled cardiovascular disease). * Incomplete medical records or imaging data, including missing required CT or MRI images.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Taichung Veterans General Hospital
Taichung, Taiwan
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Other studies related to the condition(s) this trial covers.
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