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New pill shows promise for thalassemia patients in early trial

NCT ID NCT03692052

First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 34 times

Summary

This study tested a drug called AG-348 in 20 adults with a type of thalassemia that doesn't require regular blood transfusions. The goal was to see if the drug could safely raise hemoglobin levels, which carry oxygen in the blood. Participants took the pill twice daily for up to 24 weeks, with some continuing for up to 10 years.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Imperial College Healthcare NHS Trust (Hammersmith Hospital)

    London, W12 0HS, United Kingdom

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • UCSF Benioff Children's Hospital Oakland

    Oakland, California, 94609, United States

  • University Health Network (Toronto General Hospital)

    Toronto, Ontario, M5G 2C4, Canada

Conditions

Explore the condition pages connected to this study.