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New PKU drug enters early human testing

NCT ID NCT07241234

First seen Nov 21, 2025 · Last updated May 22, 2026 · Updated 30 times

Summary

This early-stage study tests a new drug called AG-181 in 20 adults with phenylketonuria (PKU), a genetic condition that causes high levels of the amino acid phenylalanine. The main goal is to check the drug's safety and how the body processes it. Participants must have a specific gene mutation and high phenylalanine levels.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Texas Southwestern Medical Center (UTSW)

    RECRUITING

    Dallas, Texas, 75390, United States

Conditions

Explore the condition pages connected to this study.