First human tests begin for experimental pain pill

This early-stage study tested the safety and how the body processes a new oral medication called AFA-281, which is being developed for neuropathic and inflammatory pain. The study involved 64 healthy volunteers who received either the drug or a placebo in single and multiple doses over several weeks. Researchers measured drug levels in the blood and monitored participants for any side effects to determine if the medication is safe enough for further testing in people with pain conditions.