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Structured exercise may improve PCOS symptoms, small trial suggests

NCT ID NCT07157371

Disease control Sponsor: Riphah International University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests whether a 25-week supervised aerobic exercise program, added to usual medication and diet, can improve hormone levels, menstrual regularity, and quality of life in 60 women with insulin-resistant PCOS. Participants are randomly assigned to either the exercise group or a control group that only receives standard care. The researchers will measure changes in brain-derived neurotrophic factor (BDNF), androgen levels, menstrual irregularity, and mental health.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
supervised structured aerobic exercise training
What this could lead to
If this works, it could show that a structured exercise program is a helpful add-on to standard care for managing PCOS symptoms.
What could go wrong
This is a small, early-stage trial with only 60 participants, so results may not apply to all women with PCOS. Exercise alone may not be enough to significantly change hormone levels or menstrual cycles.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

60 people

The number who actually took part.

Started

Apr 2025

Expected to finish

Oct 2025

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 35 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 18 To 35 years Females. * Insulin resistant PCOS type. * Already Diagnosed patients form gynecological department according to the Rotterdam criteria. * Both Married and unmarried females. * Nulliparous females. Exclusion Criteria: * Post pill PCOS, Inflammatory PCOS \& Adrenal PCOS * Any psychological disease or disorder * Any systemic disease other than PCOS (cushing syndrome, thyroid dysfunction, etc) * Orthopedic conditions (including fracture, dislocation, etc) * Any surgery in past 6 months. * Involved in any other exercise regimen at the same time. * Having any specialized diet plan.

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Conditions

The condition(s) this trial relates to.

metabolic syndrome X polycystic ovary syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Aerobic exercise Polycystic ovarian syndrome (PCOS) Walking

Contacts and locations

Locations

  • Sculpture Gym

    Lahore, 53710, Pakistan

More trials for these conditions

Other studies related to the condition(s) this trial covers.