Gene therapy for wet AMD: how do eyes hold up years later?

NCT ID NCT04645212

Ongoing Disease control Sponsor: Adverum Biotechnologies, Inc. Source: ClinicalTrials.gov ↗

First seen Feb 12, 2026 · Last updated May 24, 2026 · Updated 14 times

Summary

This study follows 23 people who received a single dose of ADVM-022 gene therapy for wet age-related macular degeneration (AMD). Researchers are checking long-term safety and whether vision improvements last. Participants are observed over time without receiving additional treatment in this study.

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Contacts and locations

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Locations

Adverum Clinical Site

Bakersfield, California, 93309, United States
Adverum Clinical Site

Beverly Hills, California, 90211, United States
Adverum Clinical Site

Lakewood, Colorado, 80228, United States
Adverum Clinical Site

Deerfield Beach, Florida, 33064, United States
Adverum Clinical Site

Reno, Nevada, 89502, United States
Adverum Clinical Site

Philadelphia, Pennsylvania, 19107, United States
Adverum Clinical Site

Nashville, Tennessee, 37203, United States
Adverum Clinical Site

Bellaire, Texas, 77401, United States
Adverum Clinical Site

The Woodlands, Texas, 77384, United States

Conditions

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NEOVASCULAR AGE-RELATED MACULAR DEGENERATION WET AGE RELATED MACULAR DEGENERATION