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Cycle-Smart workouts may ease MS fatigue

NCT ID NCT06925022

Symptom relief Sponsor: Universidad de Almeria Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jul 30, 2026 · Updated 3 times

Summary

This study looks at whether strength training done during a specific phase of the menstrual cycle can reduce fatigue and improve quality of life in women with relapsing-remitting multiple sclerosis. Twenty women with MS and a matched group without MS will take part. Researchers will measure fatigue, energy, pain, and satisfaction with physical activity to see if personalized exercise timing makes a difference.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
strength training sessions timed to the early follicular phase of the menstrual cycle
What this could lead to
If it works, this could point toward personalized exercise programs that help women with MS manage fatigue and feel better day-to-day.
What could go wrong
This is a very small, early-stage study with only 20 participants, so results may not apply to everyone. The intervention is just exercise, not a new drug, so any benefit is likely modest.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

20 people

The number who actually took part.

Started

Dec 2024

Finished

Jun 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 50 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion criteria include: * Women of reproductive age (18-50 years) with MS will be included, with the upper age limit adjusted to reflect the reproductive phase;. * No iron-deficiency anemia. * Stable disease phase. * Independent walking ability for over 10 meters. Women will be recruited first and later matched with men based on age, EDSS, and lifestyle habits (physical activity, smoking, and alcohol consumption). Exclusion criteria will include participants with MS who: * Score \<1 or \>6 on the EDSS. * Report a relapse within 12 months before the study begins. * Have taken corticosteroid treatment within the last 2 months. * Have participated in a structured training program in the previous 6 months. Once all women with MS are recruited, male participants will be recruited following a 1:1 matching methodology based on age, geographic region, and lifestyle habits.

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Conditions

The condition(s) this trial relates to.

Motor Activity multiple sclerosis relapsing-remitting multiple sclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Multiple sclerosis (MS) - relapsing-remitting

Contacts and locations

Locations

  • Hospital Universitario Virgen de la Arrixaca

    Murcia, Murcia, 30120, Spain

More trials for these conditions

Other studies related to the condition(s) this trial covers.