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New targeted therapy duo enters human trials for advanced breast cancer

NCT ID NCT07121244

First seen Nov 01, 2025 · Last updated Jun 16, 2026 · Updated 31 times

Summary

This early-phase study tests two related drugs: one to help see tumors on scans (68Ga-R11228) and another to deliver radiation directly to cancer cells (177Lu-R11228). It is for people with advanced hormone-receptor positive breast cancer that has spread or come back. The main goal is to check safety and find the right dose in about 62 participants.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Indiana University Melvin and Bren Simon Cancer Center

    RECRUITING

    Indianapolis, Indiana, 46202, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • MD Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Email: •••••@•••••

  • Melbourne Theranostic Innovation Centre (MTIC)

    RECRUITING

    Melbourne, Australia

    Contact Email: •••••@•••••

  • United Theranostics

    RECRUITING

    Glen Burnie, Maryland, 21061, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • United Theranostics Princeton

    RECRUITING

    Princeton, New Jersey, 08540, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University Hospital Seidman Cancer Center

    RECRUITING

    Cleveland, Ohio, 44106, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Utah - Huntsman Cancer Institute

    RECRUITING

    Salt Lake City, Utah, 84112, United States

    Contact Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

hormone receptor-positive breast cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.