Can a simpler glue for braces prevent ugly white spots?
NCT ID NCT07753512
First seen Aug 07, 2026 · Last updated Aug 11, 2026 · Updated 2 times
Summary
This trial tests whether different adhesive systems used to attach braces affect the development of white spot lesions—early signs of tooth decay around the brackets. Healthy patients aged 12 to 30 undergoing full-mouth fixed braces will have brackets bonded using either a self-etch, one-step, or conventional three-step adhesive. The goal is to see which method leads to fewer white spots and less demineralisation of the teeth.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Two different adhesive systems used to bond braces: a self-etch adhesive and a one-step adhesive, compared with the conventional three-step bonding technique.
- What this could lead to
- If one adhesive system proves better, it could point toward a simpler way to reduce white spot damage around braces during orthodontic treatment.
- What could go wrong
- This is a small, early-stage trial, so results may not apply to everyone. The outcome depends on many factors, and the difference between adhesives may be small.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 34 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jan 2027
An estimate. Start dates often move.
- Expected to finish
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Jun 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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12 to 30 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * healthy patients 12-30 yrs * patients undergoing fixed appliance treatment with full mouth bonding * presence of at least 7 accessible teeth * no cavitated lesion at time of bond up Exclusion Criteria: * patients with chronic or systematic diseases * patients with fluorosis or enamel defects * presence of fixed prosthesis * patients on medications which could alter salivary flow * patients with history of salivary gland disease
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Foundation University College of Dentistry and Hospital
Islamabad, Federal, 44000, Pakistan
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