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Could bendy joints be a clue in ADHD?

NCT ID NCT07663383

Knowledge-focused Sponsor: Antalya Training and Research Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether children with ADHD are more likely to have very flexible joints (benign joint hypermobility) and if a certain blood marker differs. Researchers will compare 171 children aged 6 to 12—some with ADHD and some without—using physical exams and blood tests. The goal is to better understand any connection between connective tissue and brain development.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If a link is found, it could point toward new screening or support strategies for children with ADHD.
What could go wrong
This is an observational study, so it cannot prove cause and effect. The results may not lead to any changes in care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

171 people

The number who actually took part.

Started

Apr 2025

Finished

Oct 2025

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population consisted of children aged 6 to 12 years, including 86 patients diagnosed with Attention-Deficit/Hyperactivity Disorder (ADHD) according to DSM-5 criteria and 85 age- and sex-matched healthy controls. Patients were recruited from the Child and Adolescent Psychiatry outpatient clinic of Antalya Training and Research Hospital. Control subjects were selected from the general pediatric outpatient department. All participants were evaluated for ADHD symptom severity, joint hypermobility, and serum prolidase levels.

Ages

6 to 12 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Children aged between 6 and 12 years * ADHD diagnosis based on DSM-5 criteria (for patient group) * Healthy children with no known psychiatric or systemic disease (for control group) * Willingness of the parents or legal guardians to participate and provide informed consent * Ability to complete the required clinical assessments (CPRS-R:S, Beighton Score, blood sample) Exclusion Criteria: * Presence of chronic systemic diseases (e.g., autoimmune disorders, connective tissue diseases, metabolic syndromes) * History of neurodegenerative or severe neurological disorders Intellectual disability or autism spectrum disorder diagnosis * Use of medications that may affect prolidase enzyme activity (e.g., corticosteroids, immunosuppressants) * Any orthopedic or musculoskeletal condition interfering with Beighton assessment * Incomplete clinical or laboratory data * Refusal to participate or lack of parental consent

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Conditions

The condition(s) this trial relates to.

attention deficit hyperactivity disorder, inattentive type attention deficit-hyperactivity disorder hypermobility spectrum disorder Joint Instability

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ADHD ADHD - attention deficit disorder with hyperactivity ADHD - combined type ADHD - inattentive type Benign joint hypermobility syndrome

Contacts and locations

Locations

  • Antalya Training and Research Hospital

    Antalya, Muratpaşa, 07100, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.