Acupuncture may slash opioid use in cancer patients
NCT ID NCT04459416
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether adding acupuncture to standard pain care can reduce the need for strong opioid painkillers in people with multiple myeloma, Hodgkin disease, or non-Hodgkin lymphoma who are getting high-dose chemotherapy. About 299 adults will be randomly assigned to receive either usual pain management alone or usual care plus acupuncture. The goal is to see if acupuncture helps control pain and other symptoms, and improves quality of life.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 3
Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.
- Participants
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299 people
The number who actually took part.
- Started
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Jun 2020
- Expected to finish
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Jun 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * age 18 or older * pathological diagnosis of MM, HD or NHL * scheduled for high dose chemotherapy for auto-HSCT in the following month (30 days) * not taking opioids regularly in the week prior to consent (one-time dosing of opioids for a painful procedure is allowed) Exclusion Criteria: * absolute neutrophil count (ANC) of \<500/μl, platelet count of \<20,000/ μl or INR \>2.0 * acupuncture within two weeks prior to HiChemo (to avoid residual effects of acupuncture) * unable to provide informed consent
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Fred Hutchinson Cancer Research Center
Seattle, Washington, 98109, United States
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Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States
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Seattle Cancel Care Alliance (Data Collection Only)
Seattle, Washington, 98109, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Bispecific antibody combo aims to deepen myeloma responses
- Can a stronger drug cocktail give older myeloma patients a better start?
- Cheap blood count ratios eyed as window into Myeloma's inflammatory grip
- Can a t-cell engager rescue myeloma that outsmarted CAR-T?
- Can myeloma treatment work without steroids?
- Double-Drug attack on Hard-to-Treat lymphomas