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Acupuncture needles take aim at long COVID brain fog

NCT ID NCT07355751

Symptom relief Sponsor: Tingting Luo Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether acupuncture can improve thinking and memory problems in people with Long COVID. 108 adults with brain fog will get real acupuncture, fake acupuncture, or no treatment for 8 weeks. Researchers will also use brain scans to see if acupuncture changes how brain networks work.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
acupuncture
What this could lead to
If it works, this could point toward a safe, drug-free way to ease brain fog and memory problems in Long COVID.
What could go wrong
This is an early-stage study with only 108 people, and it uses sham acupuncture as a placebo, so any benefit might be small or not real. Acupuncture effects can vary widely.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 108 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

May 2026

An estimate. Start dates often move.

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 60 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 18-60 years * Fulfilling WHO criteria for long COVID * History of confirmed COVID-19 through RT-PCR of nasopharyngeal swab or antigen test of nasal swab ; * Having subjective cognitive problems * Native Chinese speakers * Right handedness * Voluntary to participate in the study and signing the informed consent form. Exclusion Criteria: * Preexisting cognitive symptoms before COVID-19 * Previous or current diagnosis of chronic conditions that may affect cognitive performances (such as neurological, psychiatric disorders, organ failure, chronic infectious diseases) * Prior loss of consciousness * History of major surgery within a year * Long-term use of drugs that may influence cognition(such as tranquilizer, antidepressant, immunosuppressor) * Previous acupuncture treatment within 3 months * Involvement of other clinical study within 4 weeks * Obesity(BMI≥28) * Sensory disorders(deafness, color blindness) * Limb dysfunction * Metal implantation * Claustrophobia * Pregnancy or lactation

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Conditions

The condition(s) this trial relates to.

long COVID-19

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Long COVID

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    2 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Chengdu University of Traditional Chinese Medicine

    Chengdu, Sichuan, 611130, China

  • Chengdu University of Traditional Chinese Medicine

    Chengdu, Sichuan, 611130, China

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