Acupuncture showdown: which needle works best for aching knees?
NCT ID NCT07665125
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested two acupuncture methods—thread-embedding and electroacupuncture—in 60 adults with knee osteoarthritis. Participants received 4 weeks of treatment plus standard care. The goal was to see which approach better reduced pain and improved knee function. Results may help guide non-drug treatment choices for chronic knee pain.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Thread-embedding acupuncture and electroacupuncture
- What this could lead to
- If it works, this could offer a non-drug option to ease knee pain and improve function in people with osteoarthritis.
- What could go wrong
- This is a small, completed trial with only 60 participants, so results may not apply to everyone. Acupuncture effects can vary, and the study does not compare against a sham or placebo group.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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60 people
The number who actually took part.
- Started
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Oct 2025
- Finished
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May 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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38 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 38 years or older. * Diagnosis of primary knee osteoarthritis according to the 1986 American - College of Rheumatology criteria. * Chronic knee pain lasting more than 6 months. * Baseline knee pain intensity of at least 5 points on the Visual Analog Scale. * No use of nonsteroidal anti-inflammatory drugs within 1 week before study enrollment. * Willingness to participate in the study and ability to provide written informed consent. Exclusion Criteria: * Systemic diseases, including rheumatoid arthritis, hematological disorders such as coagulation disorders or platelet dysfunction, severe cardiovascular disease such as heart failure or unstable angina, systemic infection, malignancy, immunodeficiency, or current use of immunosuppressive medication or anticoagulant medication. * Acute knee arthritis with swelling or knee joint effusion. * Peripheral platelet count less than 150,000/mm³. * Pregnancy or breastfeeding. * Alcohol abuse or substance dependence. * Intra-articular corticosteroid or hyaluronic acid injection into the affected knee within 6 months before study enrollment. * History of knee surgery or knee arthroscopy. * Signs of knee joint infection, including swelling, heat, redness, and systemic inflammatory response. * Severe radiographic knee osteoarthritis, Kellgren-Lawrence grade 4. * History of allergy, anaphylaxis, or contraindication to thread-embedding acupuncture or electroacupuncture according to the Vietnamese Ministry of Health technical guidance for traditional medicine procedures, including acute illness, severe debility, pregnancy, inflammatory or dermatological lesions at the treatment site, or allergy to absorbable thread.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Dong Nai Traditional Medicine Hospital
Đông Nãi, Bien Hoa, 76139, Vietnam
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