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Chewing gum or acupressure could replace painkillers for braces pain, study suggests

NCT ID NCT07638644

Symptom relief Sponsor: Bahria University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This trial compares three simple methods to ease pain after getting braces tightened: acupressure (pressing a spot on the hand), ibuprofen, and chewing sugar-free gum. 105 people aged 15 to 35 will be randomly assigned to one of the three groups. They will rate their pain over the first week and report if they need extra pain medicine. The goal is to find a safe, effective way to manage discomfort without relying solely on medication.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
acupressure, ibuprofen, and chewing gum
What this could lead to
If successful, this could offer patients simple, low-cost options to manage pain after getting braces tightened.
What could go wrong
This is a small, early-stage trial with only 105 participants. Results may not apply to everyone, and pain relief may be modest.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 105 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jul 2026

An estimate. Start dates often move.

Expected to finish

Jul 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

15 to 35 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 15 to 35 years * Complete permanent dentition * Undergoing comprehensive fixed orthodontic treatment * Scheduled for initial archwire placement * Ability to comply with study procedures * Written informed consent provided (or parental/guardian consent for participants younger than 18 years) Exclusion Criteria: * Pregnant or lactating * Systemic disorders that may affect pain perception * Periodontal disease * Neurological abnormalities that may affect pain perception * Known sensitivity to chewing gum * Documented allergy to ibuprofen * Use of adjunctive orthodontic appliances * Use of analgesics, anti-inflammatory medications, or other medications that may affect pain perception within 24 hours before enrollment

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Conditions

The condition(s) this trial relates to.

Malocclusion

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Malocclusion

How to take part

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  1. The official record

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